Haematology normal values
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Normal values (or reference ranges) generally approximate the 95% confidence limits of values seen in healthy people (some are age specific)
Most laboratory methods are standardised, however variations may occur
Clinicians should assess individual results using the ranges quoted by the laboratory performing the test
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Red cells
Haemoglobin (male): 130-180 g/L
Haemoglobin (female): 120-165 g/L
RBC (male): 4.5-6.5 x 10^12/L
RBC (female): 3.8-5.8 x 10^12/L
PCV (male): 0.40-0.54
PCV (female): 0.37-0.47
MCV: 80-100 fL
MCH: 27-32 pg/cell
MCHC: 300-360 g/L
Reticulocytes: 10-90 x 10^9/L (0.2-2.0%)
White cells
WBC: 4.0-11.0 x 10^9/L
Neutrophils: 2.0-7.5 x 10^9/L (54-67% WBC)
Neutrophils - bands: 0.7 x 10^9/L (3-5% WBC)
Lymphocytes: 1.5-4.0 x 10^9/L (23-33%)
Monocytes: 0.2-0.8 x 10^9/L (3-7%)
Eosinophils: 0.04-0.45 x 10^9/L (1-3%)
Basophils: 40-900 x 10^6/L (0-1%)
CD4: 0.4-1.5 x 10^9/L
Coagulation parameters
platelets: 150-400 x 10^9/L
MPV: 7.4-10.4 fL
PT: 13-17 s
APTT: 20-35 s
TCT: 11-18 s
Bleeding time: 2-9 minutes
Fibrinogen: 1.7-4.2 g/L
Antithrombin: 0.8-1.2 kIU/L
INR: 0.9-1.2
The following table sets out anticoagulant therapeutic ranges (targets) for common conditions and circumstances.
Condition
APTT
INR
Surgical conditions
1.5 - 2.5 x baseline*
2.0 - 3.0
DVT, PE, AF, AMI
2.0 - 3.0
Tissue cardiac valve replacement (first 3 months)
2.0 - 3.0
Aortic mechanical bileaflet valve replacement
2.5 - 3.5
Other mechanical cardiac valves
3.0 - 4.5
Antiphospholipid antibody syndrome
2.0 - 3.0
* APTT is only useful for monitoring IV heparin administration.
Miscellaneous
ESR (male): age ÷ 2
ESR (female): (age + 10) ÷ 2
blood viscosity: 1.50 - 1.72 cP
Related items
External links
RCPA manual of use and interpretation of pathology tests The main purpose of this online manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results. From the Royal College of Pathologists of Australasia (www.rcpamanual.edu.au).
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